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NEK2 Polyclonal Antibody, 20ul Micro Centrifuge Tubes Knockout mice lacking this gene

SKU: 59350077477

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NEK2 Polyclonal Antibody, 20ul Micro Centrifuge Tubes Knockout mice lacking this geneThis gene encodes a serine threonine protein kinase that is involved in mitotic regulation. This protein is localized to the centrosome, and undetectable during G1 phase, but accumulates progressively throughout the S phase, reaching maximal levels in late G2 phase. Alternatively spliced transcript variants encoding different isoforms with distinct C termini have been noted for this gene.

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Description

Knockout mice lacking this gene exhibit abnormalities related to development and reproduction

This gene encodes an enzyme which catalyzes the translocation of the Man(5)GlcNAc (2)-PP-Dol intermediate from the cytoplasmic to the luminal side of the endoplasmic reticulum membrane in the pathway for the N-glycosylation of proteins

Multiple transcript variants encoding different isoforms have been found for CLK1

Potent inhibitor of cellular proliferation

RPL14 (ribosomal protein L14) encodes a ribosomal protein that is a component of the 60S subunit

NEK2 Polyclonal Antibody, 20ul Micro Centrifuge Tubes Knockout mice lacking this geneThis gene encodes a serine threonine protein kinase that is involved in mitotic regulation. This protein is localized to the centrosome, and undetectable during G1 phase, but accumulates progressively throughout the S phase, reaching maximal levels in late G2 phase. Alternatively spliced transcript variants encoding different isoforms with distinct C termini have been noted for this gene.

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