Histone H2B(Phospho Ser32) Polyclonal Antibody, 50ul Microplate Mixer Multiple alternatively spliced variants have

Multiple alternatively spliced variants have been found in normal and cancerous tissues

Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains and are clustered in a region on chromosome 17q21

and has been shown to play an inhibitory role in TRAIL-induced cell apoptosis

Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2

Belongs to the MMP37 family

Histone H2B(Phospho Ser32) Polyclonal Antibody, 50ul Microplate Mixer Multiple alternatively spliced variants haveHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures.