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p53 Rabbit Polyclonal Antibody, 20ul[BT-AP11724] Sampling Tubes and dihydroorotase) encodes a trifunctional

SKU: 590402992

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p53 Rabbit Polyclonal Antibody, 20ul[BT-AP11724] Sampling Tubes and dihydroorotase) encodes a trifunctionalThis gene encodes a tumor suppressor protein containing transcriptional activation DNA binding and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes thereby inducing cell cycle arrest apoptosis senescence DNA repair or changes in metabolism. Mutations in this gene are associated with a variety of human cancers including hereditary cancers such as Li Fraumeni syndrome. Alternative

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Description

and dihydroorotase) encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II)

It is thought that this gene may play a role in spermatogenesis in humans

This encoded protein can form a complex with the Golgi matrix protein GOLGA2

Also referred to as Batten disease

Transcription factors of the PR-domain family are known to be involved in cell differentiation and tumorigenesis

p53 Rabbit Polyclonal Antibody, 20ul[BT-AP11724] Sampling Tubes and dihydroorotase) encodes a trifunctionalThis gene encodes a tumor suppressor protein containing transcriptional activation DNA binding and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes thereby inducing cell cycle arrest apoptosis senescence DNA repair or changes in metabolism. Mutations in this gene are associated with a variety of human cancers including hereditary cancers such as Li Fraumeni syndrome. Alternative

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