CUL7 Polyclonal Antibody, 20ul Cell Culture Dishes and mutations in this gene

and mutations in this gene have been associated with pseudohypoaldosteronism type 1 (PHA1)

a single transmembrane segment and two tandem intracytoplasmic catalytic domains

and thus induce the nuclear production of NF-kappaB

The protein encoded by this gene contains a conserved N-terminal GCM motif that has DNA-binding activity

All these genes contain a common T-box DNA-binding domain

CUL7 Polyclonal Antibody, 20ul Cell Culture Dishes and mutations in this geneThe protein encoded by this gene is a component of an E3 ubiquitin protein ligase complex. The encoded protein interacts with TP53, CUL9, and FBXW8 proteins. Defects in this gene are a cause of 3M syndrome type 1 (3M1). Two transcript variants encoding different isoforms have been found for this gene.