WBS22 Rabbit Polyclonal Antibody, 20ul RNA Synthesis PubMed: 22135286)

PubMed: 22135286)

PPP1R1B encodes a bifunctional signal transduction molecule

Hence this gene is one of the candidates for sex-determining gene(s) on chr 9

Chromosome Y also contains a pair of closely related genes in another more telomeric palindrome as well as several related pseudogenes

An important paralog of RABEP2 is RABEP1

WBS22 Rabbit Polyclonal Antibody, 20ul RNA Synthesis PubMed: 22135286)This gene encodes a protein containing a nuclear localization signal and an S adenosyl L methionine binding motif typical of methyltransferases suggesting that the encoded protein may act on DNA methylation. This gene is deleted in Williams syndrome a multisystem developmental disorder caused by the deletion of contiguous genes at 7q11. 23. Alternatively spliced transcript variants have been found.