HLA-DOBeta Polyclonal Antibody, 50ul Variant Libraries and the accumulation of insoluble

and the accumulation of insoluble dipeptide repeat protein aggregates that could be pathogenic in FTD-ALS patients (PMID: 23393093)

2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits

This complex acts as the molecular motor that provides the force to move cilia in an ATP-dependent manner

tissue specificity:Isoform 1 is widely expressed (brain

(PMID: 20173098 ) From BLAST result

HLA-DOBeta Polyclonal Antibody, 50ul Variant Libraries and the accumulation of insolubleHLA DOB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DOA) and a beta chain (DOB), both anchored in the membrane. It is located in intracellular vesicles. DO suppresses peptide loading of MHC class II molecules by inhibiting HLA DM. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26 28