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APS Polyclonal Antibody, 50ul Cell Culture The protein encoded by this

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APS Polyclonal Antibody, 50ul Cell Culture The protein encoded by thisThe SH2B adaptor protein 2 encoded by SH2B2 is expressed in B lymphocytes and contains pleckstrin homology and src homology 2 (SH2) domains. In Burkitt's lymphoma cell lines, it is tyrosine phosphorylated in response to B cell receptor stimulation. Because it binds Shc independent of stimulation and Grb2 after stimulation, it appears to play a role in signal transduction from the receptor to the Shc Grb2 pathway.

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Description

The protein encoded by this gene is a membrane protein involved in the regulation of planar cell polarity

a rare autosomal recessive disorder

This gene encodes the alpha-1D subunit

This protein and VP16 both bind to the same site on host cell factor C1

This protein may be involved in the onset of pain associated with peripheral neuropathy

APS Polyclonal Antibody, 50ul Cell Culture The protein encoded by thisThe SH2B adaptor protein 2 encoded by SH2B2 is expressed in B lymphocytes and contains pleckstrin homology and src homology 2 (SH2) domains. In Burkitt's lymphoma cell lines, it is tyrosine phosphorylated in response to B cell receptor stimulation. Because it binds Shc independent of stimulation and Grb2 after stimulation, it appears to play a role in signal transduction from the receptor to the Shc Grb2 pathway.

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