Rat Heparanase, HPA ELISA Kit, 96T Cell Culture Plates Expression of the encoded protein

Expression of the encoded protein is elevated in lung tumor tissue and in response to UV irradiation

stress response and maintenance of the mitochondria

HSF4 lacks the carboxyl-terminal hydrophobic repeat which is shared among all vertebrate HSFs and has been suggested to be involved in the negative regulation of DNA binding activity

may contribute to adult respiratory stress syndrome

Required during embryogenesis for extension of the primary anterior-posterior axis and for outgrowth of limbs and the genital tubercle (PubMed: 10021340)

Rat Heparanase, HPA ELISA Kit, 96T Cell Culture Plates Expression of the encoded proteinEndoglycosidase that cleaves heparan sulfate proteoglycans (HSPGs) into heparan sulfate side chains and core proteoglycans. Participates in extracellular matrix (ECM) degradation and remodeling. Selectively cleaves the linkage between a glucuronic acid unit and an N sulfo glucosamine unit carrying either a 3 O sulfo or a 6 O sulfo group. Can also cleave the linkage between a glucuronic acid unit and an N sulfo glucosamine unit carrying a 2 O sulfo