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Cadherin-23 Polyclonal Antibody, 50ul Custom DNA Oligos induction:By MYC overexpression in a

SKU: 56854836760

4.5
SEK162.00 SEK182.00

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Cadherin-23 Polyclonal Antibody, 50ul Custom DNA Oligos induction:By MYC overexpression in aCDH23 (cadherin related 23) is a member of the cadherin superfamily, whose genes encode calcium dependent cell cell adhesion glycoproteins. The encoded protein is thought to be involved in stereocilia organization and hair bundle formation. CDH23 is located in a region containing the human deafness loci DFNB12 and USH1D. Usher syndrome 1D and nonsyndromic autosomal recessive deafness DFNB12 are caused by allelic mutations of this cadherin like gene.

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Description

induction:By MYC overexpression in a concentration dependent manner in neuroblastoma cell line

including Greig cephalopolysyndactyly syndrome

Binds to SERTAD3/RBT1

The intercellular adhesion molecule 2 encoded by ICAM2 is a member of the intercellular adhesion molecule (ICAM) family

The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1)

Cadherin-23 Polyclonal Antibody, 50ul Custom DNA Oligos induction:By MYC overexpression in aCDH23 (cadherin related 23) is a member of the cadherin superfamily, whose genes encode calcium dependent cell cell adhesion glycoproteins. The encoded protein is thought to be involved in stereocilia organization and hair bundle formation. CDH23 is located in a region containing the human deafness loci DFNB12 and USH1D. Usher syndrome 1D and nonsyndromic autosomal recessive deafness DFNB12 are caused by allelic mutations of this cadherin like gene.

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