PLCA Polyclonal Antibody, 50ul Bio-Reaction Tube Alternative splicing of KRT13 results

Alternative splicing of KRT13 results in multiple transcript variants

Since the gene for this enzyme maps close to that for Duchenne muscular dystrophy| it may play a role in that disease also

Mutations of this gene have been associated with variety of inherited chondrodysplasias

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while importin-beta mediates translocation through the nuclear pore complex

PLCA Polyclonal Antibody, 50ul Bio-Reaction Tube Alternative splicing of KRT13 resultsThis gene encodes an enzyme that converts lysophosphatidic acid (LPA) into phosphatidic acid (PA). LPA and PA are two phospholipids involved in signal transduction and in lipid biosynthesis in cells. This enzyme localizes to the endoplasmic reticulum. This gene is located in the class III region of the human major histocompatibility complex. Alternative splicing results in two transcript variants encoding the same protein.