EGFR Polyclonal Antibody, 100ul[BT-AP15380] Glassware it acts as a co-activator

it acts as a co-activator for several transcription factors

Alternative promoter usage and splicing of this gene leads to two different isoforms: the mitochondrial UNG1 and the nuclear UNG2

Family members are characterized by an extended extracellular region with a variable number of N-terminal epidermal growth factor (EGF)-like domains coupled to a TM7 domain via a mucin-like spacer domain

They are expressed in nearly all cells

and vertebrates contain classes 3-7

EGFR Polyclonal Antibody, 100ul[BT-AP15380] Glassware it acts as a co-activatorThe protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.