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SHIP-2 Polyclonal Antibody, 100ul Protein Post-translational Modification BinCARD plays a role in

SKU: 5630545635

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SHIP-2 Polyclonal Antibody, 100ul Protein Post-translational Modification BinCARD plays a role inPhosphatidylinositol 3,4,5 trisphosphate 5 phosphatase 2 encoded by INPPL1 is an SH2 containing 5' inositol phosphatase that is involved in the regulation of insulin function. The encoded protein also plays a role in the regulation of epidermal growth factor receptor turnover and actin remodelling. Additionally, this gene supports metastatic growth in breast cancer and is a valuable biomarker for breast cancer.

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Description

BinCARD plays a role in inhibiting the effects of Bcl10-induced activation of NFκB possibly by inhibiting the phosphorylation of Bcl10 in a CARD-dependent manner

Antiapoptotic protein BCL2-associated athanogene 4 (BAG4/SODD) and adaptor proteins TRADD and TRAF2 have been shown to interact with this receptor

This gene encodes a subunit of NADH:ubiquinone oxidoreductase (complex I)

Mutations in this gene cause the autosomal recessive leukocyte adhesion deficiency syndrome-III (LAD-III)

three epidermal growth factor (EGF)-like domains and three fibronectin type III repeats

SHIP-2 Polyclonal Antibody, 100ul Protein Post-translational Modification BinCARD plays a role inPhosphatidylinositol 3,4,5 trisphosphate 5 phosphatase 2 encoded by INPPL1 is an SH2 containing 5' inositol phosphatase that is involved in the regulation of insulin function. The encoded protein also plays a role in the regulation of epidermal growth factor receptor turnover and actin remodelling. Additionally, this gene supports metastatic growth in breast cancer and is a valuable biomarker for breast cancer.

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