SF3A3 Polyclonal Antibody, 50ul Bottle-Top Dispenser Mouse and rat homologs have

Mouse and rat homologs have been identified and studies of the homologous rat protein indicate a role in directing TGN localization of furin by binding to the protease's phosphorylated cytosolic domain

BRF1 encodes one of the three subunits of the RNA polymerase III transcription factor complex

and belongs to the mitochondrial porin family

An important paralog of this gene is GPR45

The rat protein stimulates the activity of some Rho GTPases in vitro

SF3A3 Polyclonal Antibody, 50ul Bottle-Top Dispenser Mouse and rat homologs haveThis gene encodes subunit 3 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre mRNA splicing. Subunit 3 interacts with subunit 1 through its amino terminus while the zinc finger domain of subunit 3 plays a role in its binding to the 15S U2 snRNP. This gene has a pseudogene on chromosome 20.