A Cyclase V/VI Polyclonal Antibody, 50ul[BT-AP00055] ssDNA Synthesis This gene is the inferred

This gene is the inferred homolog of the Saccharomyces cerevisiae carboxymethyltransferase gene PPM2 that is essential for the synthesis of the hypermodified guanosine Wybutosine (yW)

Evidence indicates that mutations in this gene are responsible for the primary defects in patients with progressive myoclonic epilepsy (EPM1)

CENPL is a subunit of a CENPH (MIM 605607)-CENPI (MIM 300065)-associated centromeric complex that targets CENPA (MIM 117139) to centromeres and is required for proper kinetochore function and mitotic progression (Okada et al

This protein localizes at cell junctions and may link cell adhesion structures to the actin cytoskeleton

The activity of this receptor is mediated by G proteins

A Cyclase V/VI Polyclonal Antibody, 50ul[BT-AP00055] ssDNA Synthesis This gene is the inferredADCY5 encodes a member (adenylate cyclase 5) of the membrane bound adenylyl cyclase enzymes. Adenylyl cyclases mediate G protein coupled receptor signaling through the synthesis of the second messenger cAMP. Activity of the encoded protein is stimulated by the Gs alpha subunit of G protein coupled receptors and is inhibited by protein kinase A, calcium and Gi alpha subunits. Single nucleotide polymorphisms in this gene may be associated with low birth