FRS3 Polyclonal Antibody, 100ul Bottles It is located within a

It is located within a homozygously deleted region of a metastatic prostate cancer

The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2

May play a direct role in a TNF-alpha signaling pathway leading to induction of cell death

This gene is regulated by the transcription factors ZNF444/EZF-2 and SP1

and also ovarian hyperstimulation syndrome

FRS3 Polyclonal Antibody, 100ul Bottles It is located within aFRS3 encodes a substrate for the fibroblast growth factor receptor. Fibroblast growth factor receptor substrate 3 is found in the peripheral plasma membrane and links fibroblast growth factor receptor stimulation to activators of Ras. Fibroblast growth factor receptor substrate 3 down regulates extracellular regulated kinase 2 through direct binding.