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I10R2 Polyclonal Antibody, 50ul Site-directed Mutagenesis This gene encodes an enzyme

SKU: 53564990169

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SEK185.00 SEK231.00

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I10R2 Polyclonal Antibody, 50ul Site-directed Mutagenesis This gene encodes an enzymeThe protein encoded by this gene belongs to the cytokine receptor family. It is an accessory chain essential for the active interleukin 10 receptor complex. Coexpression of this and IL10RA proteins has been shown to be required for IL10 induced signal transduction. This gene and three other interferon receptor genes, IFAR2, IFNAR1, and IFNGR2, form a class II cytokine receptor gene cluster located in a small region on chromosome 21.

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Description

This gene encodes an enzyme that localizes to the Golgi apparatus| where it transfers an acetyl group to the N-terminus of free proteins

Alternatively spliced variants encoding different isoforms have been identified

Alternatively-spliced transcript variants have been observed

this interaction is thought to link LMP1-mediated B lymphocyte transformation to the signal transduction from TNFR family receptors

this interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation

I10R2 Polyclonal Antibody, 50ul Site-directed Mutagenesis This gene encodes an enzymeThe protein encoded by this gene belongs to the cytokine receptor family. It is an accessory chain essential for the active interleukin 10 receptor complex. Coexpression of this and IL10RA proteins has been shown to be required for IL10 induced signal transduction. This gene and three other interferon receptor genes, IFAR2, IFNAR1, and IFNGR2, form a class II cytokine receptor gene cluster located in a small region on chromosome 21.

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