Mouse Peroxisome Proliferator-activated Receptor Gamma Coactivator 1 Alpha, PGC1A ELISA Kit , 96T Cell Screening and Imaging Mutations in this gene and/or

Mutations in this gene and/or its regulatory regions cause ahaptoglobinemia or hypohaptoglobinemia

via facilitating BCAR1 and SMAD2 and/or SMAD3 interaction (By similarity)

a noncatalytic beta subunit

However the human cDNA encoding a 700 amino acid protein with a peroxisomal targeting C-terminal tripeptide S-K-L was isolated and is thought to be expressed under special conditions such as specific developmental stages or in a tissue specific manner in tissues that have not yet been examined

Multiple alternatively spliced transcript variants have been determined for this gene

Mouse Peroxisome Proliferator-activated Receptor Gamma Coactivator 1 Alpha, PGC1A ELISA Kit , 96T Cell Screening and Imaging Mutations in this gene and/orTranscriptional coactivator for steroid receptors and nuclear receptors. Greatly increases the transcriptional activity of PPARG and thyroid hormone receptor on the uncoupling protein promoter. Can regulate key mitochondrial genes that contribute to the program of adaptive thermogenesis. Plays an essential role in metabolic reprogramming in response to dietary availability through coordination of the expression of a wide array of genes involved in