MSH3 Polyclonal Antibody, 50ul Molecular Biology The nucleoporin protein encoded by

The nucleoporin protein encoded by this gene displays evolutionarily conserved interactions with other nucleoporins

|PTM:Polyubiquitination seems to allow p105 processing

This gene represents a candidate tumor suppressor gene for human breast cancer based on its location within a minimal region of chromosome 17q21 previously defined by tumor deletion mapping

CK1 Ser/Thr protein kinase family and Casein kinase I subfamily

The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor

MSH3 Polyclonal Antibody, 50ul Molecular Biology The nucleoporin protein encoded byDNA mismatch repair protein Msh3 encoded by MSH3 forms a heterodimer with MSH2 to form MutS beta, part of the post replicative DNA mismatch repair system. MutS beta initiates mismatch repair by binding to a mismatch and then forming a complex with MutL alpha heterodimer. This gene contains a polymorphic 9 bp tandem repeat sequence in the first exon. The repeat is present 6 times in the reference genome sequence and 3 7 repeats have been reported.