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Txk Polyclonal Antibody, 100ul Molecular Sciences Members of this gene family

SKU: 52391273235

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PLN123.75 PLN170.75

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Txk Polyclonal Antibody, 100ul Molecular Sciences Members of this gene familyThe Tec family of non receptor tyrosine kinases is composed of six proteins designated Tec, Emt (also known as Itk or Tsk), Btk (previously known as Atk, BPK or Emb), Bmx, Txk (also known as Rlk) and Dsrc28C. All members of the family contain SH3 and SH2 domains and, with the exception of Txk and Dsrc28C, also contain a pleckstrin homology (PH) and a Tec homology (TH) domain in their amino termini. Four alternatively spliced forms of Tec are found to

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Description

Members of this gene family are large with many exons but the CDS lengths are usually less than 3700 nt

PAK family members are known to be effectors of Rac/Cdc42 GTPases

Mutations in this gene can also cause autosomal dominant deafness 6 (DFNA6)

but the full-length nature of only three of them have been determined to date

The protein encoded by this gene is found as a pentamer and is a major substrate for the cAMP-dependent protein kinase in cardiac muscle

Txk Polyclonal Antibody, 100ul Molecular Sciences Members of this gene familyThe Tec family of non receptor tyrosine kinases is composed of six proteins designated Tec, Emt (also known as Itk or Tsk), Btk (previously known as Atk, BPK or Emb), Bmx, Txk (also known as Rlk) and Dsrc28C. All members of the family contain SH3 and SH2 domains and, with the exception of Txk and Dsrc28C, also contain a pleckstrin homology (PH) and a Tec homology (TH) domain in their amino termini. Four alternatively spliced forms of Tec are found to

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