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4E-BP1 Monoclonal Antibody, 50ul[BT-MCA0091] Bio-Reaction Tube somatic hypermutation and recombination of

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4E-BP1 Monoclonal Antibody, 50ul[BT-MCA0091] Bio-Reaction Tube somatic hypermutation and recombination ofThis gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV

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Description

somatic hypermutation and recombination of immunoglobulin genes

5-trisphosphate (IP3)-mediated Ca2+ release

Dysregulation of this gene plays a role in multiple immune-mediated diseases including lupus

When the gene product is added to the spliceosome complex

The encoded protein is a GAP shown to regulate two GTPases involved in protein trafficking and cell growth

4E-BP1 Monoclonal Antibody, 50ul[BT-MCA0091] Bio-Reaction Tube somatic hypermutation and recombination ofThis gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV

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