UN13B Rabbit Polyclonal Antibody, 20ul Peripheral Blood Separation Tube and proteolytic processing significantly affect
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UN13B Rabbit Polyclonal Antibody, 20ul Peripheral Blood Separation Tube and proteolytic processing significantly affectThis gene is expressed in the kidney cortical epithelial cells and is upregulated by hyperglycemia. The encoded protein shares a high level of similarity to the rat homolog and contains 3 C2 domains and a diacylglycerol binding C1 domain. Hyperglycemia increases the levels of diacylglycerol which has been shown to induce apoptosis in cells transfected with this gene and thus contribute to the renal cell complications of hyperglycemia. Studies in other
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