Septin 1 Polyclonal Antibody, 100ul Capsule Filter it localizes to the cytoplasm

it localizes to the cytoplasm of dendrites and is also enriched in the nucleus where it interacts with the RNA polymerase III transcriptional repressor Maf1 to regulate gamma-aminobutyric acid A receptor surface expression

as well as by the forkhead transcription factor FKHR-L1

it is possible that this gene plays an important role in the development of the cochlea and vestibulum

cell signaling survival

Decreases in expression of this protein and/or mutations in its gene have been associated with gallbladder carcinomas

Septin 1 Polyclonal Antibody, 100ul Capsule Filter it localizes to the cytoplasmSEPT1 is a member of the septin family of GTPases. Members of this family are required for cytokinesis and the maintenance of cellular morphology. SEPT1 encodes Septin 1 that can form homo and heterooligomeric filaments, and may contribute to the formation of neurofibrillary tangles in Alzheimer's disease. Alternatively spliced transcript variants have been found but the full length nature of these variants has not been determined.