CD32 Polyclonal Antibody, 50ul[BT-AP07393] Plasmid Preparation This gene is associated with

This gene is associated with X-linked mental retardation and neuropsychiatric diseases such as Huntington's chorea

Specifically

Dok-4 (Downstream of kinase-4) is a 326 amino acid protein that contains one PH domain and one IRS-type PTB domain and belongs to the Dok family of interacting proteins

Mutations in this gene have been associated with autosomal recessive non-syndromic deafness and Usher Syndrome

tissue specificity:Ubiquitously expressed with higher expression found in heart and placenta

CD32 Polyclonal Antibody, 50ul[BT-AP07393] Plasmid Preparation This gene is associated withThe Fc fragment of IgG receptor IIb encoded by FCGR2B is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene.