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Neu Polyclonal Antibody, 50ul[BT-AP05904] PCR Series Each gap junction channel is

SKU: 51209462037

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Neu Polyclonal Antibody, 50ul[BT-AP05904] PCR Series Each gap junction channel isERBB2 encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. Receptor tyrosine protein kinase erbB 2 has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase mediated activation of downstream signalling pathways, such as those

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Description

Each gap junction channel is formed by docking of 2 hemichannels

subcellular location:Present in the major dense line of CNS myelin

and reduction in gene expression was shown in colorectal cancers (PMID: 17982127)

GO annotations related to this gene include chromatin binding

This kinase binds to TRAF2 and stimulates NF-kappaB activity

Neu Polyclonal Antibody, 50ul[BT-AP05904] PCR Series Each gap junction channel isERBB2 encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. Receptor tyrosine protein kinase erbB 2 has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase mediated activation of downstream signalling pathways, such as those

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