PTPZeta Polyclonal Antibody, 50ul Aspirating Pipets HECT domain E3 ubiquitin ligases

HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates

The encoded protein forms a stoichiometric complex with the mTOR kinase

This gene is located on the long arm of chromosome 13

and homologs exist in yeast

Mutations in this gene are the cause of autosomal dominant Robinow syndrome

PTPZeta Polyclonal Antibody, 50ul Aspirating Pipets HECT domain E3 ubiquitin ligasesPTPRZ1 encodes a member of the receptor protein tyrosine phosphatase family. Expression of PTPRZ1 is restricted to the central nervous system (CNS), and it may be involved in the regulation of specific developmental processes in the CNS. Alternatively spliced transcript variants encoding different isoforms have been described for PTPRZ1.