Human Serine Threonine-protein Phosphatase PP1-alpha Catalytic Subunit, PPP1CA ELISA Kit, 96T Site-directed Mutagenesis Downregulation of expression of this

Downregulation of expression of this gene by promoter hypermethylation has been observed in a wide spectrum of human malignancies

Find maximum stability by storing at 2-8℃

Mediates the proteasomal targeting of misfolded or accumulated proteins for degradation by binding (via UBA domain) to their polyubiquitin chains and by interacting (via ubiquitin-like domain) with the subunits of the proteasome (PubMed: 15147878)

This gene encodes a protein that contains a WD-40 domain| and is thought to be involved in diphthamide biosynthesis

May also be involved in pre-mRNA splicing

Human Serine Threonine-protein Phosphatase PP1-alpha Catalytic Subunit, PPP1CA ELISA Kit, 96T Site-directed Mutagenesis Downregulation of expression of this