LIS1 Rabbit Polyclonal Antibody, 100ul Purification Beta subunits are important regulators

Beta subunits are important regulators of alpha subunits

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serves several important biosynthetic pathways

The encoded protein has been shown to control the cellular level of FBXL7| a protein that induces mitotic arrest| by targeting it for polyubiquitylation and proteasomal degradation

Mutations in this gene are associated with ataxia telangiectasia| an autosomal recessive disorder

LIS1 Rabbit Polyclonal Antibody, 100ul Purification Beta subunits are important regulatorsThis locus was identified as encoding a gene that when mutated or lost caused the lissencephaly associated with Miller Dieker lissencephaly syndrome. This gene encodes the non catalytic alpha subunit of the intracellular Ib isoform of platelet activating factor acteylhydrolase a heterotrimeric enzyme that specifically catalyzes the removal of the acetyl group at the SN 2 position of platelet activating factor (identified as 1 O alkyl 2 acetyl sn