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Rat Growth Differentiation Factor 11, GDF11 ELISA Kit, 96T Adeno-associated Virus Packaging This gene encodes alpha tubulin

SKU: 50698018604

4.4
PLN185.49 PLN232.49

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Rat Growth Differentiation Factor 11, GDF11 ELISA Kit, 96T Adeno-associated Virus Packaging This gene encodes alpha tubulinSecreted signal that acts globally to specify positional identity along the anterior posterior axis during development. May play critical roles in patterning both mesodermal and neural tissues and in establishing the skeletal pattern. Signals through activin receptors type 2, ACVR2A and ACVR2B, and activin receptors type 1, ACVR1B, ACVR1C and TGFBR1 leading to the phosphorylation of SMAD2 and SMAD3.

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Description

This gene encodes alpha tubulin and is highly similar to the mouse and rat Tuba1 genes

plays an important role in cytoskeleton reorganization

Also degrades an aberrant frameshifted 40-residue form of NPPA (fsNPPA) which is associated with familial atrial fibrillation in heterozygous patients (By similarity)

This protein is reported to be involved in the degradation of cyclin-dependent kinase inhibitor CDKN1B/p27Kip1

formerly Hallervorden-Spatz syndrome

Rat Growth Differentiation Factor 11, GDF11 ELISA Kit, 96T Adeno-associated Virus Packaging This gene encodes alpha tubulinSecreted signal that acts globally to specify positional identity along the anterior posterior axis during development. May play critical roles in patterning both mesodermal and neural tissues and in establishing the skeletal pattern. Signals through activin receptors type 2, ACVR2A and ACVR2B, and activin receptors type 1, ACVR1B, ACVR1C and TGFBR1 leading to the phosphorylation of SMAD2 and SMAD3.

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