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P53 Polyclonal Antibody, 50ul[BT-AP06811] Gel & Buffers In addition| protein levels decrease

SKU: 50429501300

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P53 Polyclonal Antibody, 50ul[BT-AP06811] Gel & Buffers In addition| protein levels decreaseTP53 (tumor protein p53) encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in TP53 are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni

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Description

In addition| protein levels decrease in the presence of natural killer lytic-associated molecule| suggesting that association with natural killer lytic-associated molecule results in ubiquitination and subsequent degradation of this protein

This enzyme differs from other beta4GalTs because it lacks the conserved Cys residues found in beta4GalT1-beta4GalT6 and it is located in cis-Golgi instead of trans-Golgi

which has anti-angiogenic and tumor suppressor properties

This gene and several other trypsinogen genes are localized to the T cell receptor beta locus on chromosome 7

this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity

P53 Polyclonal Antibody, 50ul[BT-AP06811] Gel & Buffers In addition| protein levels decreaseTP53 (tumor protein p53) encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in TP53 are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni

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