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Rock-1 Polyclonal Antibody, 50ul[BT-AP07968] Variant Libraries Pharmacologic studies have determined that

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Rock-1 Polyclonal Antibody, 50ul[BT-AP07968] Variant Libraries Pharmacologic studies have determined thatROCK1 encodes a protein serine threonine kinase that is activated when bound to the GTP bound form of Rho. The small GTPase Rho regulates formation of focal adhesions and stress fibers of fibroblasts, as well as adhesion and aggregation of platelets and lymphocytes by shuttling between the inactive GDP bound form and the active GTP bound form. Rho is also essential in cytokinesis and plays a role in transcriptional activation by serum response factor.

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Description

Pharmacologic studies have determined that cysteinyl leukotrienes activate at least 2 receptors

Specification: 1

Opioid binding protein/cell adhesion molecule like is proteolytically processed to generate the mature protein

Two transcript variants| only one of them protein-coding| have been found for this gene

Pseudogenes of this gene are located on chromosomes 1

Rock-1 Polyclonal Antibody, 50ul[BT-AP07968] Variant Libraries Pharmacologic studies have determined thatROCK1 encodes a protein serine threonine kinase that is activated when bound to the GTP bound form of Rho. The small GTPase Rho regulates formation of focal adhesions and stress fibers of fibroblasts, as well as adhesion and aggregation of platelets and lymphocytes by shuttling between the inactive GDP bound form and the active GTP bound form. Rho is also essential in cytokinesis and plays a role in transcriptional activation by serum response factor.

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