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p40-phox(Phospho Thr154) Polyclonal Antibody, 50ul Monoclonal Antibodies The alpha-3 subunit lacks the

SKU: 50073117872

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p40-phox(Phospho Thr154) Polyclonal Antibody, 50ul Monoclonal Antibodies The alpha-3 subunit lacks theThe protein encoded by this gene is a cytosolic regulatory component of the superoxide producing phagocyte NADPH oxidase, a multicomponent enzyme system important for host defense. This protein is preferentially expressed in cells of myeloid lineage. It interacts primarily with neutrophil cytosolic factor 2 (NCF2 p67 phox) to form a complex with neutrophil cytosolic factor 1 (NCF1 p47 phox), which further interacts with the small G protein RAC1 and

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Description

The alpha-3 subunit lacks the transactivation domain found in factors containing either the alpha-1 or alpha-2 subunits

The encoded adhesion protein is found in cochlear outer hair cells and appears to be important for proper hearing over an extended frequency range

A putative pseudogene exists on chromosome 12

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Within brain

p40-phox(Phospho Thr154) Polyclonal Antibody, 50ul Monoclonal Antibodies The alpha-3 subunit lacks theThe protein encoded by this gene is a cytosolic regulatory component of the superoxide producing phagocyte NADPH oxidase, a multicomponent enzyme system important for host defense. This protein is preferentially expressed in cells of myeloid lineage. It interacts primarily with neutrophil cytosolic factor 2 (NCF2 p67 phox) to form a complex with neutrophil cytosolic factor 1 (NCF1 p47 phox), which further interacts with the small G protein RAC1 and

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