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Erbin Rabbit Polyclonal Antibody, 20ul[BT-AP09695] Antisense Oligonucleotides Besides the central nervous system

SKU: 49894267805

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Erbin Rabbit Polyclonal Antibody, 20ul[BT-AP09695] Antisense Oligonucleotides Besides the central nervous systemThis gene is a member of the leucine rich repeat and PDZ domain (LAP) family. The encoded protein contains 17 leucine rich repeats and one PDZ domain. It binds to the unphosphorylated form of the ERBB2 protein and regulates ERBB2 function and localization. It has also been shown to affect the Ras signaling pathway by disrupting Ras Raf interaction. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

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Description

Besides the central nervous system

This protein may regulate neuronal proliferation and has been implicated in the progression of glioblastoma through its ability to dephosphorylate the p53 tumor suppressor

anionic phospholipids and oxidized LDL

Plasmid vectors have been constructed utilizing the MBP domain that allow the synthesis of high levels of MBP-fusion proteins that can be purified in a one step procedure by affinity chromatography cross linked amylose resin

May play a role in memory consolidation

Erbin Rabbit Polyclonal Antibody, 20ul[BT-AP09695] Antisense Oligonucleotides Besides the central nervous systemThis gene is a member of the leucine rich repeat and PDZ domain (LAP) family. The encoded protein contains 17 leucine rich repeats and one PDZ domain. It binds to the unphosphorylated form of the ERBB2 protein and regulates ERBB2 function and localization. It has also been shown to affect the Ras signaling pathway by disrupting Ras Raf interaction. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

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