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MPO Polyclonal Antibody, 100ul Molecular Biologyn The protein encoded by this

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MPO Polyclonal Antibody, 100ul Molecular Biologyn The protein encoded by thisMyeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of neutrophils.

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Description

The protein encoded by this gene binds to the fibronectin type III domains of ITGB4 and may help link ITGB4 to the intermediate filament cytoskeleton

suggesting that it may participate in redox regulation of the enzyme

childhood leukemia (t(19

At least three alternatively spliced transcripts encoding two distinct isoforms have been found for this gene

the C-terminal kinase domain binds to its own N-terminal region

MPO Polyclonal Antibody, 100ul Molecular Biologyn The protein encoded by thisMyeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of neutrophils.

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