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IRF-3 Polyclonal Antibody, 20ul[BT-AP04628] Human Genome Knockout Libraries most of which are necessary

SKU: 49497087962

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IRF-3 Polyclonal Antibody, 20ul[BT-AP04628] Human Genome Knockout Libraries most of which are necessaryIRF3 encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed

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Description

most of which are necessary for proper CEP55 function

C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit

which are encoded by distinct genes

The BARD1/BRCA1 interaction is disrupted by tumorigenic amino acid substitutions in BRCA1

ADCY7 encodes a membrane-bound adenylate cyclase that catalyses the formation of cyclic AMP from ATP and is inhibitable by calcium

IRF-3 Polyclonal Antibody, 20ul[BT-AP04628] Human Genome Knockout Libraries most of which are necessaryIRF3 encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed

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