GCKR Polyclonal Antibody, 50ul Human Genome Knockout Libraries and it may have a

and it may have a physiological role in regulating ADP-ribosylation factor protein 6 (ARF) functions

inhibits VAV1 activation upon TCR engagement and imposes a requirement for CD28 costimulation for proliferation and IL-2 production

and cytoplasmic signaling proteins

It associates with Ret to transduce Ret-mediated processes such as axonal projection

and invasion

GCKR Polyclonal Antibody, 50ul Human Genome Knockout Libraries and it may have aGCKR encodes glucokinase regulator belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non covalently to form an inactive complex with the enzyme. GCKR is considered a susceptibility gene candidate for a form of maturity onset diabetes of the young (MODY).