FAF1 Polyclonal Antibody, 100ul[BT-AP03131] Modification Enzymes tissue specificity:Highly expressed in brain

tissue specificity:Highly expressed in brain

The encoded protein is thought to be a transcriptional coactivator

subunit:Interacts with both NF-kappa-B inhibitor alpha (NFKBIA) and beta (NFKBIB) in vitro

The encoded protein may function in regulation of alternative splicing and may play a role in the pathophysiology of myotonic dystrophy

This protein may select cystic fibrosis transmembrane conductance regulator protein (CFTR) for degradation as well as unfolded proteins in Alzheimer's disease

FAF1 Polyclonal Antibody, 100ul[BT-AP03131] Modification Enzymes tissue specificity:Highly expressed in brainInteraction of Fas ligand (TNFSF6) with the FAS antigen (TNFRSF6) mediates programmed cell death, also called apoptosis, in a number of organ systems. FAS associated factor 1 encoded by FAF1 binds to FAS antigen and can initiate apoptosis or enhance apoptosis initiated through FAS antigen. Initiation of apoptosis by the protein encoded by this gene requires a ubiquitin like domain but not the FAS binding domain.