UBP6 Polyclonal Antibody, 50ul sgRNA Oligos is a nuclear receptor protein

is a nuclear receptor protein that in humans is encoded by the THRB gene

The encoded protein functions through direct interaction with target mRNAs and by disrupting the maturation of certain miRNAs involved in embryonic development

tissue specificity:Highly expressed in brain and liver

It also plays a role in the WNT and PI3K signaling pathways

Alternative splicing of PITPNB results in multiple transcript variants

UBP6 Polyclonal Antibody, 50ul sgRNA Oligos is a nuclear receptor proteinCatalytic activity: Ubiquitin C terminal thioester + H(2)O = ubiquitin + a thiol.,disease: Involved in tumorigenesis.,Has an ATP independent isopeptidase activity, cleaving at the C terminus of the ubiquitin moiety. In vitro, isoform 2, but not isoform 3, shows deubiquitinating activity.,miscellaneous: The USP6 gene only exists in the primate lineage.,Belongs to the peptidase C19 family.,Contains 1 Rab GAP TBC domain.,tissue specificity: Testis