LRAT Polyclonal Antibody, 20ul Drug Development and Evaluation Expression of ADCK2 inversely correlates

Expression of ADCK2 inversely correlates with cellular viability

This gene is expressed in cardiac cells and is required for proper heart development

It is thought that this protein may be involved in oocyte maturation and follicular development as a homodimer or by forming heterodimers with a related protein

The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3)

Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner

LRAT Polyclonal Antibody, 20ul Drug Development and Evaluation Expression of ADCK2 inversely correlatesLecithin retinol acyltransferase encoded by LRAT localizes to the endoplasmic reticulum, where it catalyzes the esterification of all trans retinol into all trans retinyl ester. This reaction is an important step in vitamin A metabolism in the visual system. Mutations in this gene have been associated with early onset severe retinal dystrophy and Leber congenital amaurosis 14. Alternative splicing results in multiple transcript variants.