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Nephrin Polyclonal Antibody, 100ul Tubes ARSI encodes a protein that

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Nephrin Polyclonal Antibody, 100ul Tubes ARSI encodes a protein thatNPHS1 encodes a member of the immunoglobulin family of cell adhesion molecules that functions in the glomerular filtration barrier in the kidney. NPHS1 is primarily expressed in renal tissues, and the protein is a type 1 transmembrane protein found at the slit diaphragm of glomerular podocytes. The slit diaphragm is thought to function as an ultrafilter to exclude albumin and other plasma macromolecules in the formation of urine. Mutations in this

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Description

ARSI encodes a protein that belongs to a large family of sulfatases that hydrolyze sulfate esters and sulfamates

Also found in early endosomes in the somatodendritic region

Mutations in COL4A1 cause porencephaly

this protein may play a role in metal homeostasis

The encoded protein is the ligand-specific component of a tripartite receptor for ciliary neurotrophic factor

Nephrin Polyclonal Antibody, 100ul Tubes ARSI encodes a protein thatNPHS1 encodes a member of the immunoglobulin family of cell adhesion molecules that functions in the glomerular filtration barrier in the kidney. NPHS1 is primarily expressed in renal tissues, and the protein is a type 1 transmembrane protein found at the slit diaphragm of glomerular podocytes. The slit diaphragm is thought to function as an ultrafilter to exclude albumin and other plasma macromolecules in the formation of urine. Mutations in this

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