FILA2 Rabbit Polyclonal Antibody, 20ul Filtration When overexpressed in cells is

When overexpressed in cells is involved in the production of sphingolipids containing different fatty acid donors (N-linked stearoyl- (C18) or arachidoyl- (C20) ceramides) in a fumonisin B1-independent manner

where it is induced by ER stress caused by malfolded proteins

the increase in capillary permeability due to contraction of terminal venules

catering to diverse testing requirements of our customers

and angiotensin II into the vasodilator angiotensin 1-7

FILA2 Rabbit Polyclonal Antibody, 20ul Filtration When overexpressed in cells isThe filaggrin like protein encoded by this gene is upregulated by calcium proteolyzed by calpain 1 and is involved in epithelial homeostasis. The encoded protein is required for proper cornification in skin with defects in this gene being associated with skin diseases. This protein also has a function in skin barrier protection. In fact in addition to providing a physical barrier C terminal fragments of this protein display antimicrobial activity