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CD57 Polyclonal Antibody, 50ul[BT-AP02069] Sample Library Tubes which plays a critical role

SKU: 47280503266

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CD57 Polyclonal Antibody, 50ul[BT-AP02069] Sample Library Tubes which plays a critical roleCOL17A1 (collagen type XVII alpha 1 chain) encodes the alpha chain of type XVII collagen. Unlike most collagens, collagen XVII is a transmembrane protein. Collagen XVII is a structural component of hemidesmosomes, multiprotein complexes at the dermal epidermal basement membrane zone that mediate adhesion of keratinocytes to the underlying membrane. Mutations in COL17A1 are associated with both generalized atrophic benign and junctional epidermolysis

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Description

which plays a critical role in nonsense-mediated mRNA decay (NMD)

N-linked glycoprotein (SIBLING) family of proteins

A ZFP91-related pseudogene has also been identified on chromosome 2

and susceptibility to osteoarthritis

Alternate splicing results in multiple transcript variants

CD57 Polyclonal Antibody, 50ul[BT-AP02069] Sample Library Tubes which plays a critical roleCOL17A1 (collagen type XVII alpha 1 chain) encodes the alpha chain of type XVII collagen. Unlike most collagens, collagen XVII is a transmembrane protein. Collagen XVII is a structural component of hemidesmosomes, multiprotein complexes at the dermal epidermal basement membrane zone that mediate adhesion of keratinocytes to the underlying membrane. Mutations in COL17A1 are associated with both generalized atrophic benign and junctional epidermolysis

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