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Parkin(Phospho Ser131) Polyclonal Antibody, 100ul sgRNA Library Construction The encoded protein regulates erythroid

SKU: 47241215066

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Parkin(Phospho Ser131) Polyclonal Antibody, 100ul sgRNA Library Construction The encoded protein regulates erythroidThe precise function of this gene is unknown; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in this gene are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of this gene produces multiple transcript variants encoding distinct isoforms. Additional splice variants

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Description

The encoded protein regulates erythroid gene expression| plays a role in the transcriptional switch of globin gene promoters| and it activates many other cellular and viral gene promoters

Histone deacetylase 1 encoded by HDAC1 belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex

and low expression in all adult tissues

Elongin A2 is specifically expressed in the testis

It is thought to be responsible for the 'local' production of T3

Parkin(Phospho Ser131) Polyclonal Antibody, 100ul sgRNA Library Construction The encoded protein regulates erythroidThe precise function of this gene is unknown; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in this gene are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of this gene produces multiple transcript variants encoding distinct isoforms. Additional splice variants

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