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PERK Polyclonal Antibody, 20ul[BT-AP07066] Cellular Function Assays REL (REL proto-oncogene

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PERK Polyclonal Antibody, 20ul[BT-AP07066] Cellular Function Assays REL (REL proto-oncogeneEukaryotic translation initiation factor 2 alpha kinase 3 encoded by EIF2AK3 phosphorylates the alpha subunit of eukaryotic translation initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. Eukaryotic translation initiation factor 2 alpha kinase 3 is thought to modulate mitochondrial function. It is a type I membrane protein located in the endoplasmic

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Description

REL (REL proto-oncogene

Mutation and knockout studies of the mouse gene demonstrated an essential role in adult spermatogenesis

This protein is a cell growth-related protein

MMEJ is an error-prone repair pathway that produces deletions of sequences from the strand being repaired and promotes genomic rearrangements

Alternative splicing occurs at DGKZ and multiple transcript variants encoding distinct isoforms have been identified

PERK Polyclonal Antibody, 20ul[BT-AP07066] Cellular Function Assays REL (REL proto-oncogeneEukaryotic translation initiation factor 2 alpha kinase 3 encoded by EIF2AK3 phosphorylates the alpha subunit of eukaryotic translation initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. Eukaryotic translation initiation factor 2 alpha kinase 3 is thought to modulate mitochondrial function. It is a type I membrane protein located in the endoplasmic

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