NOP14 Polyclonal Antibody, 20ul ADME Serine/threonine-protein kinase LATS1/2 encoded by

Serine/threonine-protein kinase LATS1/2 encoded by LATS1 is a putative serine/threonine kinase that localizes to the mitotic apparatus and complexes with cell cycle controller CDC2 kinase in early mitosis

Mutations in this gene are associated with aspirin-induced susceptibility to asthma

serves as the scaffold for assembly of the remainder of the transcription complex

Mutations in GATA4 have been associated with cardiac septal defects

Three related pseudogenes are located within the Smith-Magenis syndrome region on chromosome 17

NOP14 Polyclonal Antibody, 20ul ADME Serine/threonine-protein kinase LATS1/2 encoded byThis gene encodes a protein that plays a role in pre 18s rRNA processing and small ribosomal subunit assembly. The encoded protein may be involved in the regulation of pancreatic cancer cell proliferation and migration. Alternative splicing results in multiple transcript variants.