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Cripto Monoclonal Antibody, 100ul DNA Libraries Synthesis This encoded protein can form

SKU: 46307822484

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Cripto Monoclonal Antibody, 100ul DNA Libraries Synthesis This encoded protein can formThis gene encodes an epidermal growth factor related protein that contains a cripto, FRL 1, and cryptic domain. The encoded protein is an extracellular, membrane bound signaling protein that plays an essential role in embryonic development and tumor growth. Mutations in this gene are associated with forebrain defects. Pseudogenes of this gene are found on chromosomes 2, 3, 6, 8, 19 and X. Alternate splicing results in multiple transcript variants.

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Description

This encoded protein can form a complex with the Golgi matrix protein GOLGA2

The encoded protein is postranslationally glycosylated and localized to the lysosome

an Src-type non-receptor tyrosine kinase

This gene may act as a tumor suppressor as it is lost in several tumor types and maps to a chromosomal region (3p14

Binding of the encoded ligand to NKG2D leads to activation of several signal transduction pathways

Cripto Monoclonal Antibody, 100ul DNA Libraries Synthesis This encoded protein can formThis gene encodes an epidermal growth factor related protein that contains a cripto, FRL 1, and cryptic domain. The encoded protein is an extracellular, membrane bound signaling protein that plays an essential role in embryonic development and tumor growth. Mutations in this gene are associated with forebrain defects. Pseudogenes of this gene are found on chromosomes 2, 3, 6, 8, 19 and X. Alternate splicing results in multiple transcript variants.

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