INSI2 Polyclonal Antibody, 100ul Insect Expression RGR may be associated with

RGR may be associated with autosomal recessive and autosomal dominant retinitis pigmentosa (arRP and adRP

Among its related pathways are Transport to the Golgi and subsequent modification and Surfactant metabolism

and is required for association with spectrin and actin

and (in human) retinal degeneration

DM1424 & DM1224

INSI2 Polyclonal Antibody, 100ul Insect Expression RGR may be associated withThe protein encoded by this gene is highly similar to the protein product encoded by gene INSIG1. Both INSIG1 protein and this protein are endoplasmic reticulum proteins that block the processing of sterol regulatory element binding proteins (SREBPs) by binding to SREBP cleavage activating protein (SCAP), and thus prevent SCAP from escorting SREBPs to the Golgi.