M3K14 Polyclonal Antibody, 100ul Plates & Dishes The shorter apoB-48 protein is

The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA)

A fairly broad range of trinucleotide repeats (9-35) has been identified in normal controls| and repeat numbers in excess of 40 have been described as pathological

The encoded protein is a single-pass type I membrane protein and contains 8 immunoglobulin-like C2-type domains

Two splice variants encoding different isoforms have been found for this gene

Neurogranin (NRGN) is the human homolog of the neuron-specific rat RC3/neurogranin gene

M3K14 Polyclonal Antibody, 100ul Plates & Dishes The shorter apoB-48 protein isThis gene encodes mitogen activated protein kinase kinase kinase 14, which is a serine threonine protein kinase. This kinase binds to TRAF2 and stimulates NF kappaB activity. It shares sequence similarity with several other MAPKK kinases. It participates in an NF kappaB inducing signalling cascade common to receptors of the tumour necrosis nerve growth factor (TNF NGF) family and to the interleukin 1 type I receptor.