Rb(Phospho Ser811) Polyclonal Antibody, 100ul Cell Separation and Collection Transiently dissociates following mitogenic stimulation

Transiently dissociates following mitogenic stimulation

Multiple transcript variants encoding different isoforms have been found for CABLES1

It contains a TFIID-31 domain

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Rb(Phospho Ser811) Polyclonal Antibody, 100ul Cell Separation and Collection Transiently dissociates following mitogenic stimulationThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.