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Flt3-L Polyclonal Antibody, 50ul[BT-AP03284] Antibody Humanization Multiple transcript variants encoding different

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Flt3-L Polyclonal Antibody, 50ul[BT-AP03284] Antibody Humanization Multiple transcript variants encoding differentDendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens and priming pathogen specific immune responses. FLT3LG controls the development of DCs and is particularly important for plasmacytoid DCs and CD8 (see MIM 186910) positive classical DCs and their CD103 (ITGAE; MIM 604682) positive tissue counterparts (summary by Sathaliyawala et al. 2010 [PubMed: 20933441]).

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Description

Multiple transcript variants encoding different isoforms have been found for CALM1

NBPF1 is a member of the neuroblastoma breakpoint family (NBPF) which consists of dozens of recently duplicated genes primarily located in segmental duplications on human chromosome 1

SEPT3 belongs to the septin family of GTPases

This gene encodes a glycosylated phosphoprotein with a leucine zipper motif| two helix-loop-helix motifs (I repeats) that are similar to domains found in the TFII-I family of transcription factors| one CHARLIE8 transposable element-like sequence| and a BED zinc finger

|PTM:Phosphorylation by PKB/AKT1 inhibits transcriptional activity and is responsible for cytoplasmic localization

Flt3-L Polyclonal Antibody, 50ul[BT-AP03284] Antibody Humanization Multiple transcript variants encoding differentDendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens and priming pathogen specific immune responses. FLT3LG controls the development of DCs and is particularly important for plasmacytoid DCs and CD8 (see MIM 186910) positive classical DCs and their CD103 (ITGAE; MIM 604682) positive tissue counterparts (summary by Sathaliyawala et al. 2010 [PubMed: 20933441]).

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