T3HPD Rabbit Polyclonal Antibody, 50ul ADME BUB3 encodes a protein involved

BUB3 encodes a protein involved in spindle checkpoint function

|Contains 1 Rho-GAP domain

The encoded protein also functions in mitochondrial DNA replication and repair

An important paralog of this gene is ZIC3

catalyzing the production of cGMP from GTP

T3HPD Rabbit Polyclonal Antibody, 50ul ADME BUB3 encodes a protein involvedThe protein encoded by this gene is a dehydratase that converts trans 3 hydroxy L proline to delta(1) pyrroline 2 carboxylate. This enzyme may function to degrade dietary proteins that contain trans 3 hydroxy L proline as well as other proteins such as collagen IV. The encoded protein can be converted to an epimerase by changing a threonine to a cysteine at a catalytic site.